“Hidden” sex differences in neurological reward pathways suggest opportunity for improved psychiatric therapeutics… (You cannot change God’s biology!)
A new study in the Journal of Neuroscience has discovered underlying sex differences in the molecular pathways that drive reward-related behaviors. In particular, the study found differences and similarities in the ways males and females strengthened connections between two brain regions—the hippocampus and the nucleus accumbens—involved in reward signaling.
Males and females both suffer from disorders involving these pathways, like depression and substance abuse. However, the presentation and prevalence of these conditions can differ between the sexes, and certain standard treatments are more effective on average in males or females. The new paper’s findings encourage further research to determine if the molecular differences the authors discovered may underpin differences in disease progression or medication response, which could eventually lead to more effective treatments for mental health disorders.
The full article is here…